Overview

Tracking the long-term safety and effectiveness of modern treatments, including biologics and JAK inhibitors, for patients with rheumatoid arthritis (RA).

The BSR RA Register (BSRBR‑RA) is a national observational study established to monitor the safety and effectiveness of biologic and targeted treatments and capture information about adverse events.

The BSRBR‑RA was established in 2001 and is run by an expert team based in the Versus Arthritis Epidemiology Unit at the University of Manchester.


Now recruiting for:



Amgevita


Benepali


Cimzia



Enbrel



Erelzi



Flixabi



Hulio



Humira



Hyrimoz



Idacio



Imraldi



Inflectra



Jyseleca



Kevzara



MabThera



Olumiant



Orencia



Remsima



Remicade



Rinvoq



Rixathon



RoActemra


Ruxience

Truxima

Tyenne


Yuflyma

Xeljanz


Patients on the register are flagged with the NHS Information Centre, which notifies the register of anyone who develops cancer plus any deaths, with their cause.

Patients with similar disease activity on conventional disease-modifying anti-rheumatic drugs and recruited in a cohort since closed still provide comparison data. The register is on the NIHR CLRN portfolio database, so there is financial support for registering patients.

If you're an NHS clinician, health professional or research network staff with a recruitment query about a patient or the treatment cohorts in rheumatoid arthritis, please get in touch.

For over 25 years, the register has shaped clinical guidelines, informed regulatory decisions, improved patient care, and generated hundreds of peer reviewed publications. Read all about the history, impact and success of this register in our 25 Year Anniversary Brochure.


BSR and the University of Manchester are committed to ensuring that this rich dataset continues to drive impactful research and improved patient care. Access to the data is open, and applications are actively welcomed from anyone with an interest in using the registers to answer important clinical or research questions. The university registers team can work with researchers to develop and deliver research ideas.

Visit study website

View published papers

Submit an enquiry

Access the BSRBR-RA data

The NIHR Principal Investigator Scheme
The BSRBR-RA and UK JIA Biologics register has signed up to a new initiative aimed at supporting the next generation of research study investigators.

Learn more about the NIHR Associate Principal Investigator Scheme - a six-month practical work training opportunity for healthcare professionals.
Find out more